First off, Foreman's brother (Orlando Jones - delightful) just got out of jail, and instead of going to drive him home, Foreman decides to put in a day's work at old Plainsboro. This, for some reason, really irks House, who decides that they should be closer. So, he takes the completely reasonable step of hiring Foreman's brother as his personal assistant, annoying Foreman to no end, which was the point in the first place. In between getting his dry cleaning and fetching him frappucinos, Foreman's brother also reveals embarrassing secrets about Foreman's youth, which House deploys to the amusement of the rest of the team. Ha, ha, ha!
Meanwhile, the patient this week is a college football player with unexplained and unremembered rage issues. At first, the team is convinced it's steroids, but the player protests that he's never taken them. The tests show he's not lying, so the team goes round and round on several diagnoses that, of course, are all proven wrong.
The secondary patient is a clinic walk-in who insists on meeting with House. Turns out he's about to be stop-lossed to the Middle East, but desperately doesn't want to go, since he has a heavily pregnant wife to take care of. House has no sympathy for him, and is offended when the soldier assumes that House's limp is from Vietnam. He suggests the soldier move to Canada or shoot his foot.
While these shenanigans are going on at the hospital, almost equally crazy things are happening at the new Casa de Wilson and House. Someone left a possum in their bathtub, loosening the grip bar by House's tub, and turned on the sprinklers in the middle of the night! Who could be behind such foul behavior? House assumes it's Foreman, getting him back for hiring his brother. In response, House rachets up Foreman's humiliation.
Once again, House's words come back to bite him in the ass, as the soldier returns, having shot his foot. House gets ready to amputate a toe, which, unfortunately, will not preclude his military duty, since he will still be able to run. The military man decides to let the infection spread to his entire foot, necessitating amputation, rather than be deployed.
Seeing the importance of family unity, House decides to completely sabotage Foreman and his brother's relationship, by revealing that the brother told House about Foreman's mother's death, something that happened only three months ago, but that he didn't share with anyone at the hospital. Foreman is pissed, and the brother is super pissed that House told, so Foreman walks out, and the brother quits. House is unfazed.
Back to the football dude. His symptoms have improved, and he's desperate to play in the big game, where all the pro scouts will be watching. Why does he feel the need to possibly die, just for a shot at the pros? Turns out he's doing it all for his mom, who gave up everything so he could play. He wants to pay her back by being able to take care of her for the rest of her life. They finally let him go, after he promises to return for treatment after the game. Foreman goes with him to make sure he's okay during the match. But, just as he's about to walk on the field, he's struck temporarily blind, and agrees to go back to the hospital and miss the game, and his shot at the big time.
Turns out that Foreman slipped him a drug in his Gatorade that caused temporary blindness, just so he'd go back with them. Oh, that Foreman! After dropping off Mr. Football at the hospital, Foreman then goes to his brother's halfway house, makes amends, and offers to let the brother move in with him. Awww, relationship mended!
They find the cause of the football player's maladies - melanoma, which no one originally diagnosed because the player is African American - and Wilson realizes that House caused the rift between the Foreman brothers only to create a common enemy (him) and ultimately bring them closer together. Awwww, House loves family! But what about the pranks at their new house? They continue, and know now that it isn't Foreman. Turns out it's Luke, Cuddy's new boyfriend, paying them back for stealing the house of her dreams. Well, they deserved it.
Yet again, House has learned an Important Lesson this episode. I'm not sure I know where this is going - if he learns how to interact with humans, where will the fun be? WHERE?